RNAi Screening Libraries
HORIZON DISCOVERY BIOSCIENCES LIMITED SV INDUCIBLE HU PAX8 SHRNA
NC3822534 SV INDUCIBLE HU PAX8 SHRNA
Cayman Chemical BLT2 Receptr PolycLNal ntI 1ea
Immunogen: peptide from the C-terminal region of human BLT2 • Host: Rabbit • Species Reactivity: (+) Human and mouse • Application(s): WB
Cayman Chemical EP Receptr asy Prostaglnd 20uL
An ionizable cationic lipid (pKa 6.39) has been used in the generation of LNPs for siRNA delivery in vitro and in vivo LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter decrease viability of HepG2 cells LNPs containing O12-D3-I3 and an mRNA reporter selectively accumulate in the tumor and liver over the lungs kidneys spleen and heart in mice LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter reduce tumor growth and volume in an MCF-7 breast cancer mouse xenograft model LNPs containing O12-D3-I3 and encapsulating siRNA targeting Factor VII decrease hepatocyte Factor VII mRNA levels in mice
Cayman Chemical Dog Pregn X Receptr Repor 96
dPXR Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields exceptional cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for cumbersome intermediate treatment steps such as spin-and-rinse of cells, viability determinations, or cell titer adjustments prior to assay setup.[INDIGO Catalog Nos. D07001-32, D07001]
Cayman Chemical Humn Strogen Receptr Alpha 96
ER Alpha Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments.[INDIGO Catalog Nos. IB00401-32, IB00401, IB00402]
Cayman Chemical sn-glycero-3-PhosphocholIn 5g
A nootropic phospholipid; a precursor to choline biosynthesis and an intermediate in the metabolism of phosphatidylcholine; increases acetylcholine synthesis and release in rat hippocampus; prevents scopolamine-induced amnesia in a passive avoidance test in rats; exerts neuroprotective effects in models of altered cholinergic neurotransmission and models of brain vascular injury
HORIZON DISCOVERY BIOSCIENCES LIMITED PIN-POINT SYNTHETIC SGRNA VALI
NC3867373 PIN-POINT SYNTHETIC SGRNA VALI
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN POU2AF1 SYNTHETIC SGRNA
NC3841485 HUMAN POU2AF1 SYNTHETIC SGRNA
Cayman Chemical MelnocortIn4 Receptr Rever 1ea
An MC4R antagonist selectively inhibits [Nle4D-Phe7]-a-MSH binding to recombinant human MC4R over MC1R and MC3R (IC50s 11.63 >10000 and 1115 nM respectively) inhibits a-MSH-induced cAMP production in COS-1 cells expressing human MC4R from 0.1-100 UM reduces stress-induced decreases in the time spent in the light area of the light/dark exploration test in mice reverses restraint stress-induced decreases in food intake in rats
